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For example, activated microglia phagocytose cellular debris, produce neurotrophic factors, and release anti-inflammatory cytokines, including TGF-β and IL-10, to aid in tissue recovery [152], yet microglia also release pro-inflammatory mediators to disrupt the blood-brain barrier, to recruit peripheral leukocytes into the injured CNS, and to evoke rapid cell death in adjacent oligodendrocytes [153–155]